Independent · Evidence-graded

Men's health, by the evidence.

Testosterone support, libido, recovery, body composition — what the research actually shows for the compounds men ask about, graded honestly.

Independent and educational. No products, no sellers — just the evidence.

Latest in the report

Stronger evidence Preliminary / mixed Weak / unreplicated
Enclomiphene

Selective estrogen receptor modulator (SERM) · Investigational (compounded only)

Enclomiphene

An estrogen-blocking molecule that prompts the body to make more of its own testosterone, studied for men with secondary low testosterone who want to preserve fertility.

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PT-141 (Bremelanotide)

Melanocortin receptor agonist · FDA-approved (women only)

PT-141 (Bremelanotide)

A brain-acting peptide that stimulates sexual desire and arousal through melanocortin receptors, FDA-approved for women but not for men.

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Tesamorelin

Growth-hormone-releasing hormone (GHRH) analog · FDA-approved (HIV lipodystrophy)

Tesamorelin

A peptide that prompts the pituitary to release the body's own growth hormone, FDA-approved specifically to reduce excess abdominal fat in adults with HIV-associated lipodystrophy.

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Gonadorelin

Gonadotropin-releasing hormone (GnRH) · Formerly FDA-approved (diagnostic; brand withdrawn)

Gonadorelin

A synthetic copy of the brain's gonadotropin-releasing hormone that tells the pituitary to release LH and FSH, historically used as a diagnostic agent.

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